You don't specify where on the body, so I am going to say yes, I had severe strep throat with my first pregnancy, when I was 2 months along. I took amoxicillin and they also gave me cough syrup with codeine, which they said would not affect the baby. Well, my baby was full term and is now a wonderful 10 year old boy, very bright and perfectly normal. If you have a bacterial infection it is 100% safe to take antibiotics, but if you don't for fear of medications, you will only spread the bacteria to your baby, and then you will see problems. P.S. Bindi: Thrush is fungal, not bacterial